DCLRE1C anticorps (C-Term)

N° du produit ABIN2784441

L’anticorps anti-DCLRE1C Polyclonal Lapin est utilisé pour la détection de DCLRE1C dans des échantillons de Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Lapin et Chien. Il a été validé pour WB.

Aperçu rapide pour DCLRE1C anticorps (C-Term) (ABIN2784441)

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DCLRE1C anticorps

Épitope: C-Term

Fonction: DCLRE1C Antibody - C-terminal region

Séquence: SQSPKLFSDS DGESTHISSQ NSSQSTHITE QGSQGWDSQS DTVLLSSQER

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against DCLRE1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DCLRE1C

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51165-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: DCLRE1C

Sujet:

Background Information: DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).

Gene Name: DNA cross-link repair 1C

Alternative Symbols: SCIDA, SNM1C, A-SCID, RS-SCID, DCLREC1C

Protein Name: Protein artemis

Poids moléculaire: 65kDa

ID gène: 64421

NCBI Accession: NP_001029029

UniProt: Q96SD1

Pathways: Réparation de l'ADN