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NAGS anticorps (C-Term)

Cet anticorps anti-NAGS est un anticorps Lapin Polyclonal détectant NAGS dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin et Poisson zèbre (Danio rerio).
N° du produit ABIN2784450

Aperçu rapide pour NAGS anticorps (C-Term) (ABIN2784450)

Antigène

Voir toutes NAGS Anticorps
NAGS (N-Acetylglutamate Synthase (NAGS))

Reactivité

  • 9
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio)

Hôte

  • 8
  • 1
Lapin

Clonalité

  • 9
Polyclonal

Conjugué

  • 9
Cet anticorp NAGS est non-conjugé

Application

  • 9
  • 4
  • 2
  • 1
Western Blotting (WB)
  • Épitope

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 534 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    NAGS (N-Acetylglutamate Synthase (NAGS))

    Autre désignation

    NAGS

    Sujet

    NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
    Alias Symbols: AGAS, ARGA, MGC133025
    Protein Interaction Partner: TMEM39B,
    Protein Size: 534

    Poids moléculaire

    58 kDa

    ID gène

    162417

    NCBI Accession

    NM_153006, NP_694551

    UniProt

    Q8N159
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