NAGS anticorps (C-Term)

N° du produit ABIN2784450

Cet anticorps anti-NAGS Polyclonal Lapin (ABIN2784450) détecte spécifiquement NAGS dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour NAGS anticorps (C-Term) (ABIN2784450)

Antigène: NAGS (N-Acetylglutamate Synthase (NAGS))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Porc, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAGS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NAGS anticorps

Épitope: C-Term

Fonction: NAGS Antibody - C-terminal region

Séquence: YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51183-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NAGS

Antigène: NAGS (N-Acetylglutamate Synthase (NAGS))

Autre désignation: NAGS

Sujet:

Background Information: NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.

Gene Name: N-acetylglutamate synthase

Alternative Symbols: AGAS, ARGA

Protein Name: N-acetylglutamate synthase, mitochondrial

Poids moléculaire: 58 kDa

ID gène: 162417

NCBI Accession: NP_694551

UniProt: Q8N159