Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps

N° du produit ABIN2784460

Cet anticorps Lapin Polyclonal détecte spécifiquement Tec Protein Tyrosine Kinase dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps (ABIN2784460)

Antigène: Tec Protein Tyrosine Kinase (TEC)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Séquence: VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TEC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 631 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Tec Protein Tyrosine Kinase (TEC)

Autre désignation: TEC

Sujet: The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Alias Symbols: MGC126760, MGC126762, PSCTK4
Protein Interaction Partner: ERBB2, MED28, GRB2, SHC1, FASLG, Nedd4, UBC, IKBKG, STAP1, PIP4K2A, PLK4, PTPN18, PIK3R3, GNA12, SOCS1, PIP5K1A, PTPN21, DOK1, TEC, PLCG2, WAS, BTK, BMX, TP53, PRLR, PLCG1, PIK3R1, LYN, KIT, VAV1, JAK2, JAK1, ARHGEF12, GNA13, RHOA, RAC1, PIK3R2,
Protein Size: 631

Poids moléculaire: 73 kDa

ID gène: 7006

NCBI Accession: NM_003215, NP_003206

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway