Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps
Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) (Middle Region) anticorps (ABIN2784460)
Antigène
Voir toutes Tec Protein Tyrosine Kinase (TEC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- TEC Antibody - middle region
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Séquence
- VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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Attributs du produit
- This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TEC
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51209-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Tec Protein Tyrosine Kinase (TEC)
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Autre désignation
- TEC
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Sujet
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Background Information: The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Gene Name: Tec protein tyrosine kinase
Alternative Symbols: PSCTK4
Protein Name: Tyrosine-protein kinase Tec
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Poids moléculaire
- 73kDa
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ID gène
- 7006
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NCBI Accession
- NP_003206
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UniProt
- P42680
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Pathways
- Fc-epsilon Receptor Signaling Pathway
Antigène
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