TNNT3 anticorps (N-Term)

N° du produit ABIN2784497

Cité dans 2 publications. Cet anticorps anti-TNNT3 Polyclonal Lapin (ABIN2784497) détecte spécifiquement TNNT3 dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Cheval, Chien, Chévre et Poisson zèbre (Danio rerio).

Aperçu rapide pour TNNT3 anticorps (N-Term) (ABIN2784497)

Antigène: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Reactivité: Humain, Souris, Rat, Cobaye, Lapin, Boeuf (Vache), Cheval, Chien, Chévre, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNNT3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNNT3 anticorps

Épitope: N-Term

Fonction: TNNT3 Antibody - N-terminal region

Séquence: PRPKLTAPKI PEGEKVDFDD IQKKRQNKDL MELQALIDSH FEARKKEEEE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNNT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TNNT3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100501

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TNNT3 (ABIN2784497)

Zhang, Pereyra, Wang, Birbrair, Reisz, Files, Purcell, Feng, Messi, Feng, Chalovich, Jin, Furdui, Delbono: "Calpain inhibition rescues troponin T3 fragmentation, increases Cav1.1, and enhances skeletal muscle force in aging sedentary mice." dans: Aging cell, Vol. 15, Issue 3, pp. 488-98, (2016) (PubMed).

Zhang, Birbrair, Delbono: "Nonmyofilament-associated troponin T3 nuclear and nucleolar localization sequence and leucine zipper domain mediate muscle cell apoptosis." dans: Cytoskeleton (Hoboken, N.J.), Vol. 70, Issue 3, pp. 134-47, (2013) (PubMed).

Détails sur TNNT3

Antigène: TNNT3 (Fast Skeletal Troponin T (TNNT3))

Autre désignation: TNNT3

Sujet:

Background Information: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Gene Name: Troponin T type 3 (skeletal, fast)

Alternative Symbols: TNTF, DA2B2, beta-TnTF

Protein Name: Troponin T, fast skeletal muscle

Poids moléculaire: 32 kDa

ID gène: 7140

NCBI Accession: NP_001036245

UniProt: P45378