CD42b anticorps (Middle Region)

N° du produit ABIN2784513

Détail du produit anti-CD42b anticorps

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Épitope: Middle Region

Reactivité: Humain, Rat, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Western Blotting (WB)

Séquence: TPTPKLEKLS LANNNLTELP AGLLNGLENL DTLLLQENSL YTIPKGFFGS

Homologie: Guinea Pig: 86%, Human: 100%, Rat: 79%

Attributs du produit: This is a rabbit polyclonal antibody against GP1BA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GP1BA

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: GP1BA (GP1BA Produits)

Synonymes: anticorps BDPLT1, anticorps BDPLT3, anticorps BSS, anticorps CD42B, anticorps CD42b-alpha, anticorps DBPLT3, anticorps GP1B, anticorps GPIbA, anticorps VWDP, anticorps GP1BA, anticorps GPIba, anticorps GPIbalpha, anticorps glycoprotein Ib platelet alpha subunit, anticorps glycoprotein Ib (platelet), alpha polypeptide, anticorps glycoprotein 1b, alpha polypeptide, anticorps GP1BA, anticorps Gp1ba

Sujet: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
Alias Symbols: BSS, GP1B, VWDP, CD42B, GPIbA, BDPLT1, BDPLT3, DBPLT3, GPIbalpha, CD42b-alpha
Protein Size: 346

Poids moléculaire: 38 kDa

ID gène: 2811

NCBI Accession: NM_000173, NP_000164

UniProt: P07359