HNF1A anticorps (N-Term)

N° du produit ABIN2784536

Cet anticorps Lapin Polyclonal détecte spécifiquement HNF1A dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Chien, Cobaye, Cheval et Boeuf (Vache) et a été mentionné dans 1 publication.

Aperçu rapide pour HNF1A anticorps (N-Term) (ABIN2784536)

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HNF1A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-HNF1A anticorps

Épitope: N-Term

Séquence: HAGQGGLIEE PTGDELPTKK GRRNRFKWGP ASQQILFQAY ERQKNPSKEE

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against HNF1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human HNF1A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 631 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-HNF1A (ABIN2784536)

Scheving, Zhang, Garcia, Wang, Stevenson, Threadgill, Russell: "Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 306, Issue 5, pp. G370-81, (2014) (PubMed).

Détails sur HNF1A

Antigène: HNF1A (HNF1 Homeobox A (HNF1A))

Autre désignation: HNF1A

Sujet: HNF1A is required for the expression of several liver specific genes. HNF1A binds to the inverted palindrome 5'-GTTAATNATTAAC-3'.
Alias Symbols: HNF1, LFB1, MODY3, TCF1, TCF-1, HNF-1A, IDDM20
Protein Interaction Partner: RNF14, RYR3, RAC3, PCBD1, HIST2H2AB, RPSAP15, SNX14, CBX3, YWHAZ, YWHAG, YWHAE, YWHAB, VIM, VCP, HNF1A, SRSF7, RANBP1, PEBP1, LDHA, IGFBP7, HMGB1, ANXA2, ACTB, SIRT1, BCL6, EP300, CREBBP, GATA5, HNF1B, KAT2B, CDX2, HNF4A, TLE1, SRC, FOS, POU2F1, BCR, CEBP
Protein Size: 631

Poids moléculaire: 67 kDa

ID gène: 6927

NCBI Accession: NM_000545, NP_000536

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis