ADA anticorps (N-Term)

N° du produit ABIN2784608

Détail du produit anti-ADA anticorps

Antigène: ADA (Adenosine Deaminase (ADA))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADA est non-conjugé

Application: Western Blotting (WB)

Séquence: AIAGCREAIK RIAYEFVEMK AKEGVVYVEV RYSPHLLANS KVEPIPWNQA

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ADA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ADA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 363 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ADA (ABIN2784608)

Ferrante, Martire, Pepponi, Varani, Vincenzi, Ferraro, Beggiato, Tebano, Popoli: "Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease." dans: Neurobiology of disease, Vol. 71, pp. 193-204, (2014) (PubMed).

Détails sur ADA

Antigène: ADA (Adenosine Deaminase (ADA))

Autre désignation: ADA (ADA Produits)

Synonymes: anticorps ADA-like, anticorps xada, anticorps ADA, anticorps CG11994, anticorps Dmel\\CG11994, anticorps DrosADA, anticorps dADA, anticorps zgc:92028, anticorps adenosine deaminase, anticorps adenosine deaminase S homeolog, anticorps Adenosine deaminase, anticorps ADA, anticorps Ada, anticorps ada.S, anticorps ada

Sujet: ADA is an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.
Alias Symbols: -
Protein Interaction Partner: UBC, SGCD, PIAS2, TERF2IP, TINF2, ADORA2B, DPP4, NR3C1, DRD1, GRB2, ADORA2A, ADORA1,
Protein Size: 363

Poids moléculaire: 41 kDa

ID gène: 100

NCBI Accession: NM_000022, NP_000013

UniProt: P00813

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process