Adrenomedullin anticorps (C-Term)

N° du produit ABIN2784687

Cet anticorps anti-Adrenomedullin Polyclonal Lapin (ABIN2784687) détecte spécifiquement Adrenomedullin dans WB. L’anticorps est réactif avec des échantillons de Humain et Lapin.

Aperçu rapide pour Adrenomedullin anticorps (C-Term) (ABIN2784687)

Antigène: Adrenomedullin (ADM)

Reactivité: Humain, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adrenomedullin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Adrenomedullin anticorps

Épitope: C-Term

Fonction: ADM Antibody - C-terminal region

Séquence: VAPRSKISPQ GYGRRRRRSL PEAGPGRTLV SSKPQAHGAP APPSGSAPHF

Homologie: Human: 100%, Rabbit: 91%

Attributs du produit: This is a rabbit polyclonal antibody against ADM. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51920-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur Adrenomedullin

Antigène: Adrenomedullin (ADM)

Autre désignation: ADM

Classe de substances: Hormone

Sujet:

Background Information: Adrenomedullin, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes. There are also multiple binding sites for activator protein-2 and a cAMP-regulated enhancer element.

Gene Name: Adrenomedullin

Alternative Symbols: AM, PAMP

Protein Name: ADM

Poids moléculaire: 20kDa

ID gène: 133

NCBI Accession: NP_001115

UniProt: P35318

Pathways: Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation