Protein Tob1 (TOB1) (Middle Region) anticorps

N° du produit ABIN2784777

L’anticorps Lapin Polyclonal anti- a été validé pour WB. Il convient pour détecter dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc et Saccharomyces cerevisiae.

Aperçu rapide pour Protein Tob1 (TOB1) (Middle Region) anticorps (ABIN2784777)

Antigène: Protein Tob1 (TOB1)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Séquence: DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TOB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 345 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Protein Tob1 (TOB1)

Autre désignation: TOB1

Sujet: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
Alias Symbols: APRO6, MGC104792, MGC34446, PIG49, TOB, TROB, TROB1
Protein Interaction Partner: CORO7, APP, DTL, CDC7, PABPC1, CHAF1A, PAN2, UBR5, ELAVL1, SMAD3, CTNNB1, UBC, SKP2, SCMH1, MARCKS, SETDB1, CNOT7, SMAD9, SMAD5, SMAD6, SMAD1, SMAD2, SMAD4, MAPK1, ERBB2, RPS6KA1, MAPK9,
Protein Size: 345

Poids moléculaire: 38 kDa

ID gène: 10140

NCBI Accession: NM_005749, NP_005740

UniProt: P50616