Protein Tob1 (TOB1) (Middle Region) anticorps

N° du produit ABIN2784777

L’anticorps anti-Protein Tob1 Polyclonal Lapin est utilisé pour la détection de Protein Tob1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc et Saccharomyces cerevisiae. Il a été validé pour WB.

Aperçu rapide pour Protein Tob1 (TOB1) (Middle Region) anticorps (ABIN2784777)

Antigène: Protein Tob1 (TOB1)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Détail du produit

Épitope: Middle Region

Fonction: TOB1 Antibody - middle region

Séquence: DLLKQKAISS SMHSLYGLGL GSQQQPQQQQ QPAQPPPPPP PPQQQQQQKT

Homologie: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 92%, Yeast: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TOB1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TOB1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52105-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détail du antigène

Antigène: Protein Tob1 (TOB1)

Autre désignation: TOB1

Sujet:

Background Information: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

Gene Name: Transducer of ERBB2, 1

Alternative Symbols: TOB, TROB, APRO5, APRO6, PIG49, TROB1

Protein Name: Protein Tob1

Poids moléculaire: 38kDa

ID gène: 10140

NCBI Accession: NP_005740

UniProt: P50616