BCKDK anticorps (N-Term)

N° du produit ABIN2784788

Cet anticorps Lapin Polyclonal détecte spécifiquement BCKDK dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Lapin et Cheval.Il a été cité dans 1 publication.

Aperçu rapide pour BCKDK anticorps (N-Term) (ABIN2784788)

Antigène: BCKDK (Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Cobaye, Lapin, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCKDK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-BCKDK anticorps

Épitope: N-Term

Fonction: BCKDK Antibody - N-terminal region

Séquence: CLPFIIGCNP TILHVHELYI RAFQKLTDFP PIKDQADEAQ YCQLVRQLLD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BCKDK. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human BCKDK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8095650

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-BCKDK (ABIN2784788)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur BCKDK

Antigène: BCKDK (Branched Chain Ketoacid Dehydrogenase Kinase (BCKDK))

Autre désignation: BCKDK

Sujet:

Background Information: BCKDK belongs to the PDK/BCKDK protein kinase family. It contains 1 histidine kinase domain. BCKDK catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. BCKDK is the key enzyme that regulates the activity state of the BCKD complex.

Gene Name: Branched chain ketoacid dehydrogenase kinase

Alternative Symbols: BDK, BCKDKD

Protein Name: [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial

Poids moléculaire: 43kDa

ID gène: 10295

NCBI Accession: NP_005872

UniProt: O14874

Pathways: SARS-CoV-2 Protein Interactome