DLC1 anticorps (C-Term)
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- Antigène Voir toutes DLC1 Anticorps
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DLC1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1
- Top Product
- Discover our top product DLC1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 467 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- DLC1 (Deleted in Liver Cancer 1 (DLC1))
- Autre désignation
- DLC1 (DLC1 Produits)
- Synonymes
- anticorps ARHGAP7, anticorps HP, anticorps STARD12, anticorps p122-RhoGAP, anticorps rhogap7, anticorps DLC-1, anticorps StARD12, anticorps Dlc-1, anticorps A730069N07Rik, anticorps Arhgap7, anticorps dlc-1, anticorps RhoGAP, anticorps Dlc1, anticorps DLC1 Rho GTPase activating protein, anticorps DLC1 Rho GTPase activating protein S homeolog, anticorps rho GTPase-activating protein 7, anticorps deleted in liver cancer 1, anticorps DLC1, anticorps dlc1.S, anticorps dlc1, anticorps LOC100456847, anticorps Dlc1, anticorps LOC100729904
- Sujet
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This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.
Alias Symbols: ARHGAP7, FLJ21120, HP, STARD12, p122-RhoGAP
Protein Interaction Partner: DDB1, FBXW5, CUL1, CUL2, CUL3, CUL4A, UBC, TENC1, CAV1, S100A10, WWC1, AKT1,
Protein Size: 467 - Poids moléculaire
- 52 kDa
- ID gène
- 10395
- NCBI Accession
- NM_001164271
- UniProt
- Q9Y238
- Pathways
- Tube Formation, Positive Regulation of Endopeptidase Activity
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