DLC1 anticorps (C-Term)

N° du produit ABIN2784792

L’anticorps anti-DLC1 Polyclonal Lapin est utilisé pour la détection de DLC1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour DLC1 anticorps (C-Term) (ABIN2784792)

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DLC1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DLC1 anticorps

Épitope: C-Term

Fonction: DLC1 Antibody - C-terminal region

Séquence: NLAVCLAPSL FHLNTLKREN SSPRVMQRKQ SLGKPDQKDL NENLAATQGL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against DLC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human DLC1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52138-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur DLC1

Antigène: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Autre désignation: DLC1

Sujet:

Background Information: This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. DLC1 functions as a GTPase-activating protein specific for Rho and an activator of PLCD1 in vivo and induces morphological changes and detachment through cytoskeletal reorganization.

Gene Name: Deleted in liver cancer 1

Alternative Symbols: HP, ARHGAP7, STARD12, p122-RhoGAP

Protein Name: Deleted in lung and esophageal cancer protein 1

Poids moléculaire: 52kDa

ID gène: 10395

UniProt: Q9Y238

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity