FBXW10 anticorps (Middle Region)

N° du produit ABIN2784922

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXW10 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Rat.

Aperçu rapide pour FBXW10 anticorps (Middle Region) (ABIN2784922)

Antigène: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW10 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXW10 anticorps

Épitope: Middle Region

Fonction: FBXW10 Antibody - middle region

Séquence: RKIHLLDIIQ VKAIPVEFRG HAGSVRALFL CEEENFLLSG SYDLSIRYWD

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 77%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXW10

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52421-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXW10

Antigène: FBXW10 (F-Box and WD Repeat Domain Containing 10 (FBXW10))

Autre désignation: FBXW10

Sujet:

Background Information: Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Gene Name: F-box and WD repeat domain containing 10

Alternative Symbols: HREP, Fbw10, SM25H2, SM2SH2

Protein Name: F-box/WD repeat-containing protein 10

Poids moléculaire: 120kDa

ID gène: 10517

NCBI Accession: NP_113644

UniProt: Q5XX13