MED8 anticorps (N-Term)

N° du produit ABIN2784933

Détail du produit anti-MED8 anticorps

Antigène: MED8 (Mediator Complex Subunit 8 (MED8))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED8 est non-conjugé

Application: Western Blotting (WB)

Séquence: MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against MED8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MED8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 301 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED8

Antigène: MED8 (Mediator Complex Subunit 8 (MED8))

Autre désignation: MED8 (MED8 Produits)

Sujet: MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase.This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
Alias Symbols: ARC32, MGC17544, MGC19641
Protein Interaction Partner: PNMA1, KRT40, CDK19, CDK8, MED19, MED26, FBXW7, EPAS1, MED29, MED18, CPSF1, MED4, MED16, MED12, MED24, MED21, MED14, MED1, HIST1H1E, APP, MED11, SUMO2, MED10, RBX1, CTDP1, CUL2, TCEB2, TCEB1, MED28, OBFC1, ZC3H13, TRIP4, TADA2A, THOC7, PHYHIP, MED20, MED9
Protein Size: 301

Poids moléculaire: 33 kDa

ID gène: 112950

NCBI Accession: NM_052877, NP_443109

Pathways: Regulation of Lipid Metabolism by PPARalpha