FBXO32 anticorps (N-Term)

N° du produit ABIN2785130

Détail du produit anti-FBXO32 anticorps

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio), Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO32 est non-conjugé

Application: Western Blotting (WB)

Séquence: QQQLNNIQIT RPAFKGLTFT DLPLCLQLNI MQRLSDGRDL VSLGQAAPDL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against FBXO32. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO32

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 210 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXO32

Antigène: FBXO32 (F-Box Protein 32 (FBXO32))

Autre désignation: FBXO32 (FBXO32 Produits)

Synonymes: anticorps MGC56479, anticorps zgc:56479, anticorps Fbx32, anticorps MAFbx, anticorps 4833442G10Rik, anticorps AI430017, anticorps ATROGIN1, anticorps Gm20361, anticorps Atrogin1, anticorps F-box protein 32, anticorps fbxo32, anticorps FBXO32, anticorps Fbxo32

Sujet: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing of this gene results in two transcript variants encoding two isoforms of different sizes.
Alias Symbols: FLJ32424, Fbx32, MAFbx, MGC33610
Protein Interaction Partner: UBC, MLH1, Mutyh, UBE2D3, KHDRBS3, SERPINB5, CDC34, DUSP1, FBXO25, MYBPC3, CDKN1A, EIF3F, SKP1, EIF3A,
Protein Size: 210

Poids moléculaire: 25 kDa

ID gène: 114907

NCBI Accession: NM_148177, NP_680482

UniProt: Q0VAQ6