IL-24 anticorps (C-Term)

N° du produit ABIN2785371

Cet anticorps anti-IL-24 est un anticorps Lapin Polyclonal détectant IL-24 dans WB. Adapté pour Humain, Rat, Souris, Chien et Cheval.

Aperçu rapide pour IL-24 anticorps (C-Term) (ABIN2785371)

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Reactivité: Humain, Rat, Souris, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL-24 anticorps

Épitope: C-Term

Séquence: STLANNFVLI VSQLQPSQEN EMFSIRDSAH RRFLLFRRAF KQLDVEAALT

Homologie: Dog: 77%, Horse: 85%, Human: 100%, Mouse: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against IL24. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of IL24

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 207 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: IL24

Sujet: This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27 kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: C49A, FISP, IL-24, IL10B, MDA7, Mob-5, ST16, mda-7, MOB5
Protein Interaction Partner: DCD, RARG, CCR5, CLU, UBC, IL20RA,
Protein Size: 207

Poids moléculaire: 22 kDa

ID gène: 11009

NCBI Accession: NM_001185156, NP_001172085

UniProt: Q53XZ7

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy