AKR1C2 anticorps (N-Term)

N° du produit ABIN2785422

L’anticorps anti-AKR1C2 Polyclonal Lapin est utilisé pour la détection de AKR1C2 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye et Mouton. Il a été validé pour WB.

Aperçu rapide pour AKR1C2 anticorps (N-Term) (ABIN2785422)

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AKR1C2 anticorps

Épitope: N-Term

Fonction: AKR1C2 Antibody - N-terminal region

Séquence: LEAVKLAIEA GFHHIDSAHV YNNEEQVGLA IRSKIADGSV KREDIFYTSK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 86%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53506-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1C2

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Autre désignation: AKR1C2

Sujet:

Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Gene Name: Aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2, bile acid binding protein, 3-alpha hydroxysteroid dehydrogenase, type III)

Alternative Symbols: DD, DD2, TDD, BABP, DD-2, DDH2, HBAB, HAKRD, MCDR2, SRXY8, DD/BABP, AKR1C-pseudo

Protein Name: Aldo-keto reductase family 1 member C2

Poids moléculaire: 37kDa

ID gène: 1646

NCBI Accession: NP_995317

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process