AKR1C2 anticorps (N-Term)

N° du produit ABIN2785423

Détail du produit anti-AKR1C2 anticorps

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKR1C2 est non-conjugé

Application: Western Blotting (WB)

Séquence: DGSVKREDIF YTSKLWSNSH RPELVRPALE RSLKNLQLDY VDLYLIHFPV

Homologie: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 90%, Pig: 100%, Rabbit: 91%, Rat: 90%

Attributs du produit: This is a rabbit polyclonal antibody against AKR1C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1C2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 323 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AKR1C2

Antigène: AKR1C2 (Aldo-keto Reductase Family 1, Member C2 (AKR1C2))

Autre désignation: AKR1C2 (AKR1C2 Produits)

Synonymes: anticorps AKR1C-pseudo, anticorps BABP, anticorps DD, anticorps DD2, anticorps DDH2, anticorps HAKRD, anticorps HBAB, anticorps MCDR2, anticorps SRXY8, anticorps Akr1c21, anticorps aldo-keto reductase family 1 member C2, anticorps aldo-keto reductase family 1, member C2, anticorps AKR1C2, anticorps Akr1c2

Sujet: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8
Protein Interaction Partner: UBC, AKR1C2,
Protein Size: 323

Poids moléculaire: 37 kDa

ID gène: 1646

NCBI Accession: NM_205845, NP_995317

UniProt: P52895

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process