GSTM3 anticorps (Middle Region)

N° du produit ABIN2785445

Détail du produit anti-GSTM3 anticorps

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSTM3 est non-conjugé

Application: Western Blotting (WB)

Séquence: SMFLGKFSWF AGEKLTFVDF LTYDILDQNR IFDPKCLDEF PNLKAFMCRF

Homologie: Cow: 79%, Dog: 79%, Goat: 75%, Guinea Pig: 79%, Horse: 77%, Human: 100%, Mouse: 86%, Pig: 85%, Rabbit: 90%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against GSTM3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GSTM3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 225 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GSTM3

Antigène: GSTM3 (Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Autre désignation: GSTM3 (GSTM3 Produits)

Synonymes: anticorps GST5, anticorps GSTB, anticorps GSTM3-3, anticorps GTM3, anticorps Fsc2, anticorps mGSTM5, anticorps glutathione S-transferase mu 3, anticorps glutathione S-transferase Mu 3, anticorps glutathione S-transferase, mu 3, anticorps GSTM3, anticorps Gstm3, anticorps LOC479911

Sujet: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. GSTM3 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GST5, GSTB, GSTM3-3, GTM3, MGC3310, MGC3704
Protein Interaction Partner: GSTM5, GSTM4, GSTM3, GSTM1, UBC, ESR1, BAG3, SUMO2, SH3GL2, UCHL5, GSTM2, MPG,
Protein Size: 225

Poids moléculaire: 26 kDa

ID gène: 2947

NCBI Accession: NM_000849, NP_000840

UniProt: P21266