CRISP1 anticorps (N-Term)

N° du produit ABIN2785457

Cet anticorps Lapin Polyclonal détecte spécifiquement CRISP1 dans WB. Il présente une réactivité avec des échantillons de Humain, Boeuf (Vache), Chévre, Porc, Lapin, Poisson zèbre (Danio rerio) et Chien.

Aperçu rapide pour CRISP1 anticorps (N-Term) (ABIN2785457)

Antigène: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Reactivité: Humain, Boeuf (Vache), Chévre, Porc, Lapin, Poisson zèbre (Danio rerio), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRISP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRISP1 anticorps

Épitope: N-Term

Fonction: CRISP1 Antibody - N-terminal region

Séquence: LKMSWSEEAA QNARIFSKYC DMTESNPLER RLPNTFCGEN MHMTSYPVSW

Homologie: Cow: 85%, Dog: 85%, Goat: 85%, Human: 100%, Pig: 85%, Rabbit: 79%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CRISP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CRISP1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53580-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CRISP1

Antigène: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Autre désignation: CRISP1

Sujet:

Background Information: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. CRISP1 is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface.Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene.

Gene Name: Cysteine-rich secretory protein 1

Alternative Symbols: ARP, AEGL1, HUMARP, CRISP-1, HEL-S-57, HSCRISP1D, HSCRISP1G

Protein Name: Cysteine-rich secretory protein 1

Poids moléculaire: 27kDa

ID gène: 167

NCBI Accession: NP_001122

UniProt: P54107