Coilin anticorps (C-Term)

N° du produit ABIN2785484

Détail du produit anti-Coilin anticorps

Antigène: Coilin (COIL)

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Coilin est non-conjugé

Application: Western Blotting (WB)

Séquence: DYSLLPLLAA APQVGEKIAF KLLELTSSYS PDVSDYKEGR ILSHNPETQQ

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Zebrafish: 82%

Attributs du produit: This is a rabbit polyclonal antibody against COIL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human COIL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 576 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Coilin

Antigène: Coilin (COIL)

Autre désignation: COIL (COIL Produits)

Synonymes: anticorps p80c, anticorps coil, anticorps CG8710, anticorps Coilin, anticorps Dmel\\CG8710, anticorps LOC100218802, anticorps F3F19.5, anticorps F3F19_5, anticorps CLN80, anticorps p80-coilin, anticorps C79982, anticorps Cln80, anticorps p80, anticorps wu:fb08h11, anticorps sph1, anticorps Coilin, anticorps coilin, anticorps sphere organelles protein-like protein, anticorps coilin p80, anticorps coilin L homeolog, anticorps p80c, anticorps COIL, anticorps coil, anticorps AT1G13030, anticorps Coil, anticorps coil.L

Sujet: COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CLN80, p80-coilin
Protein Interaction Partner: MFAP1, FGF12, BYSL, WDR34, ZCCHC10, ARMCX1, ZNF277, PDLIM5, CDC23, SNRPF, PTS, POLR2L, PDE4D, DRG1, WWOX, UBL5, CSNK2A2, UBC, VCP, TAF9, LACTB2, KYNU, SMN2, SMN1, GTF2F1, APP, UBD, PLEKHG4, KAZN, PSME3, FAM115A, SART3, PREPL, FXR2, PICK1, FHL5, DNAJA3, KA
Protein Size: 576

Poids moléculaire: 63 kDa

ID gène: 8161

NCBI Accession: NM_004645, NP_004636

UniProt: P38432

Pathways: Ribonucleoprotein Complex Subunit Organization