FGFR1OP anticorps (N-Term)

N° du produit ABIN2785509

Cet anticorps Lapin Polyclonal détecte spécifiquement FGFR1OP dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval et Cobaye.

Aperçu rapide pour FGFR1OP anticorps (N-Term) (ABIN2785509)

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGFR1OP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FGFR1OP anticorps

Épitope: N-Term

Fonction: FGFR1OP Antibody - N-terminal region

Séquence: FLQFFNLDFT LAVFQPETST LQGLEGRENL ARDLGIIEAE GTVGGPLLLE

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FGFR1OP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FGFR1OP

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100613

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur FGFR1OP

Antigène: FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))

Autre désignation: FGFR1OP

Sujet:

Background Information: FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

Gene Name: FGFR1 oncogene partner

Alternative Symbols: FOP, FGFR1OP

Protein Name: FGFR1 oncogene partner

Poids moléculaire: 41kDa

ID gène: 11116

NCBI Accession: NP_919410

UniProt: O95684

Pathways: M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interactome