GLA anticorps (N-Term)

N° du produit ABIN2785641

L’anticorps Lapin Polyclonal anti-GLA a été validé pour WB. Il convient pour détecter GLA dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Chévre, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour GLA anticorps (N-Term) (ABIN2785641)

Antigène: GLA (Galactosidase, alpha (GLA))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Chévre, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GLA anticorps

Épitope: N-Term

Séquence: PQRFPHGIRQ LANYVHSKGL KLGIYADVGN KTCAGFPGSF GYYDIDAQTF

Homologie: Cow: 93%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against GLA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human GLA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 429 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GLA

Antigène: GLA (Galactosidase, alpha (GLA))

Autre désignation: GLA

Sujet: GLA is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GALA
Protein Interaction Partner: ZNF622, CNDP2, MAT2B, EIF4H, PGD, GNS, GBP2, G6PD, EIF5, CAPN1, ALDH7A1, TERT, UBC, FBXO6, OTUD4, GLA,
Protein Size: 429

Poids moléculaire: 45 kDa

ID gène: 2717

NCBI Accession: NM_000169, NP_000160

UniProt: P06280

Pathways: SARS-CoV-2 Protein Interactome