LIG1 anticorps (Middle Region)

N° du produit ABIN2785647

L’anticorps anti-LIG1 Polyclonal Lapin est utilisé pour la détection de LIG1 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval et Porc. Il a été validé pour WB.

Aperçu rapide pour LIG1 anticorps (Middle Region) (ABIN2785647)

Antigène: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIG1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LIG1 anticorps

Épitope: Middle Region

Fonction: LIG1 Antibody - middle region

Séquence: PSVTSFILDT EAVAWDREKK QIQPFQVLTT RKRKEVDASE IQVQVCLYAF

Homologie: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 92%, Rabbit: 85%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LIG1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human LIG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54308-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur LIG1

Antigène: LIG1 (Ligase I, DNA, ATP-Dependent (LIG1))

Autre désignation: LIG1

Sujet:

Background Information: This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Gene Name: DNA ligase 1

Protein Name: DNA ligase 1

Poids moléculaire: 102kDa

ID gène: 3978

NCBI Accession: NP_000225

UniProt: P18858

Pathways: Telomere Maintenance, Réparation de l'ADN, DNA Replication, Synthesis of DNA