SH3KBP1 anticorps (N-Term)

N° du produit ABIN2785720

Détail du produit anti-SH3KBP1 anticorps

Antigène: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Cobaye, Boeuf (Vache), Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3KBP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: TGMFPSNFIK ELSGESDELG ISQDEQLSKS SLRETTGSES DGGDSSSTKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SH3KBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SH3KBP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 628 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SH3KBP1

Antigène: SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))

Autre désignation: SH3KBP1 (SH3KBP1 Produits)

Synonymes: anticorps CD2BP3, anticorps CIN85, anticorps GIG10, anticorps HSB-1, anticorps HSB1, anticorps MIG18, anticorps 1200007H22Rik, anticorps 1700125L08Rik, anticorps 5830464D22Rik, anticorps AI447724, anticorps IN85, anticorps Ruk, anticorps Seta, anticorps SH3 domain containing kinase binding protein 1, anticorps SH3-domain kinase binding protein 1, anticorps SH3 domain-containing kinase-binding protein 1, anticorps SH3KBP1, anticorps sh3kbp1, anticorps LOC100551401, anticorps Sh3kbp1

Sujet: This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants.
Alias Symbols: CIN85, GIG10, MIG18, HSB1, HSB-1, CD2BP3
Protein Interaction Partner: PNMA5, ZBTB7B, SH3KBP1, STAP1, FRS3, SPRY2, ASAP2, PSMA3, CBL, UBC, RAF1, LOX, INPP5D, Dlg4, FAP, ARHGAP17, Ap2a1, Irf2bp1, Gcdh, Sept7, Wipf1, Chtf8, Cblb, Shkbp1, Rtkn2, Idh3b, Pik3ap1, Slc25a12, Wasl, Ap2b1, Arap1, Far1, Cltc, Timm50, Actn4, Sept6, Net
Protein Size: 628

Poids moléculaire: 68 kDa

ID gène: 30011

NCBI Accession: NM_001024666, NP_001019837

UniProt: Q5JPT5

Pathways: EGFR Signaling Pathway, EGFR Downregulation