UBE4B anticorps (N-Term)

N° du produit ABIN2785770

Cet anticorps anti-UBE4B Polyclonal Lapin (ABIN2785770) détecte spécifiquement UBE4B dans WB. L’anticorps est réactif avec des échantillons de Humain, Chien et Porc.

Aperçu rapide pour UBE4B anticorps (N-Term) (ABIN2785770)

Antigène: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Reactivité: Humain, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE4B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-UBE4B anticorps

Épitope: N-Term

Fonction: UBE4B Antibody - N-terminal region

Séquence: SPMFCSVASF GASSLSSLYE SSPAPTPSFW SSVPVMGPSL ASPSRAASQL

Homologie: Dog: 79%, Human: 100%, Pig: 79%

Attributs du produit: This is a rabbit polyclonal antibody against UBE4B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54552-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE4B

Antigène: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Autre désignation: UBE4B

Sujet:

Background Information: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: Ubiquitination factor E4B

Alternative Symbols: E4, UFD2, HDNB1, UBOX3, UFD2A

Protein Name: Ubiquitin conjugation factor E4 B

Poids moléculaire: 146kDa

ID gène: 10277

NCBI Accession: NP_001099032

UniProt: O95155