UBE4B anticorps (N-Term)

N° du produit ABIN2785770

Détail du produit anti-UBE4B anticorps

Antigène: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Épitope: N-Term

Reactivité: Humain, Chien, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE4B est non-conjugé

Application: Western Blotting (WB)

Séquence: SPMFCSVASF GASSLSSLYE SSPAPTPSFW SSVPVMGPSL ASPSRAASQL

Homologie: Dog: 79%, Human: 100%, Pig: 79%

Attributs du produit: This is a rabbit polyclonal antibody against UBE4B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE4B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1302 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE4B

Antigène: UBE4B (Ubiquitin Conjugation Factor E4 B (UBE4B))

Autre désignation: UBE4B (UBE4B Produits)

Synonymes: anticorps ufd2a, anticorps E4, anticorps HDNB1, anticorps UBOX3, anticorps UFD2, anticorps UFD2A, anticorps 4930551I19Rik, anticorps 4933406G05Rik, anticorps AU014668, anticorps D4Bwg0973e, anticorps UFD2a, anticorps Ufd2p, anticorps mKIAA0684, anticorps ubiquitination factor E4B, anticorps putative ubiquitin conjugation factor E4 B, anticorps ubiquitin conjugation factor E4 B, anticorps ubiquitination factor E4B, UFD2 homolog (S. cerevisiae), anticorps Ube4b, anticorps LINJ_30_1070, anticorps LBRM_30_1130, anticorps Tsp_12732, anticorps Tsp_01624, anticorps ube4b, anticorps UBE4B

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE4B is an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. The gene that encodes the protein is also the strongest candidate in the neuroblastoma tumor suppressor genes. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: E4, HDNB1, KIAA0684, UBOX3, UFD2, UFD2A
Protein Interaction Partner: TRIP12, UBC, FBXW11, HGS, STAM, TP53, MDM2, NUSAP1, NUDCD3, RBM12, PDE3A, CDKN2A, UBL7, UBE2D3, CDC27, TTK, IGBP1, HDLBP, TTC9C, MRPL53, ZFYVE19, SARNP, SRPRB, VPS35, UBA6, VPS29, UFM1, SBDS, VPS36, UBQLN1, UBXN7, UBE2C, AHCYL1, SSSCA1, SF3B4, PPIF, SCO2,
Protein Size: 1302

Poids moléculaire: 146 kDa

ID gène: 10277

NCBI Accession: NM_001105562, NP_001099032

UniProt: O95155