FES anticorps (N-Term)

N° du produit ABIN2785796

L’anticorps Lapin Polyclonal anti-FES a été validé pour WB. Il convient pour détecter FES dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache), Porc et Poisson zèbre (Danio rerio).

Aperçu rapide pour FES anticorps (N-Term) (ABIN2785796)

Antigène: FES (Feline Sarcoma Oncogene (FES))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Lapin, Boeuf (Vache), Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FES est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FES anticorps

Épitope: N-Term

Séquence: ARDSAQAKRK YQEASKDKDR DKAKDKYVRS LWKLFAHHNR YVLGVRAAQL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 88%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against FES. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human FES

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 822 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FES

Antigène: FES (Feline Sarcoma Oncogene (FES))

Autre désignation: FES

Sujet: FES is the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. FES has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FPS
Protein Interaction Partner: MDFI, HSP90AA1, EGFR, UBC, TRIM28, POT1, TERF1, NEDD4, ZNF775, ZNF746, PDE4DIP, HSH2D, PLXNA1, DPYSL5, RASA3, BCAR1, DOK1, IRS2, JAK3, FES, PIK3R1, BCR, JAK2, JAK1, IL4R, IRS1, RASA1, CSF2RB, STAT3, PTGES3, PPID, HSPA4, FKBP5, FKBP4, PSMD13,
Protein Size: 822

Poids moléculaire: 93 kDa

ID gène: 2242

NCBI Accession: NM_002005, NP_001996

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2