INHBA anticorps (N-Term)

N° du produit ABIN2785821

Cet anticorps anti-INHBA est un anticorps Lapin Polyclonal détectant INHBA dans WB. Adapté pour Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chien, Chévre et Lapin. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour INHBA anticorps (N-Term) (ABIN2785821)

Antigène: INHBA (Inhibin, beta A (INHBA))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chien, Chévre, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INHBA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-INHBA anticorps

Épitope: N-Term

Séquence: CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against INHBA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human INHBA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 426 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-INHBA (ABIN2785821)

Ndiaye, Castonguay, Benoit, Silversides, Lussier: "Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." dans: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).

Détails sur INHBA

Antigène: INHBA (Inhibin, beta A (INHBA))

Autre désignation: INHBA

Sujet: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Alias Symbols: EDF, FRP
Protein Interaction Partner: ACVRL1, ACVR2B, ACVR2A, ACVR1, FST, IGSF1, CHRDL2, FSTL3, IGFBP7, ACVR1B, INHBC, TGFBR3, INHBB, INHA, INHBA, ENG,
Protein Size: 426

Poids moléculaire: 44 kDa

ID gène: 3624

NCBI Accession: NM_002192, NP_002183

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy