INHBA anticorps (N-Term)

N° du produit ABIN2785821

Cité dans 1 publication. Cet anticorps anti-INHBA Polyclonal Lapin (ABIN2785821) détecte spécifiquement INHBA dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chévre, Chien et Lapin.

Aperçu rapide pour INHBA anticorps (N-Term) (ABIN2785821)

Antigène: INHBA (Inhibin, beta A (INHBA))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chévre, Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INHBA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-INHBA anticorps

Épitope: N-Term

Fonction: INHBA Antibody - N-terminal region

Séquence: CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against INHBA. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human INHBA

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54663-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-INHBA (ABIN2785821)

Ndiaye, Castonguay, Benoit, Silversides, Lussier: "Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." dans: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).

Détails sur INHBA

Antigène: INHBA (Inhibin, beta A (INHBA))

Autre désignation: INHBA

Sujet:

Background Information: The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.

Gene Name: Inhibin, beta A

Alternative Symbols: EDF, FRP

Protein Name: Inhibin beta A chain

Poids moléculaire: 44kDa

ID gène: 3624

NCBI Accession: NP_002183

UniProt: P08476

Pathways: Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy