INHBA anticorps (N-Term)
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- Antigène Voir toutes INHBA Anticorps
- INHBA (Inhibin, beta A (INHBA))
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Épitope
- N-Term
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chévre, Chien, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp INHBA est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL
- Homologie
- Cow: 100%, Dog: 93%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against INHBA. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human INHBA
- Top Product
- Discover our top product INHBA Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 426 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." dans: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).
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Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." dans: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).
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- Antigène
- INHBA (Inhibin, beta A (INHBA))
- Autre désignation
- INHBA (INHBA Produits)
- Synonymes
- anticorps EDF, anticorps FRP, anticorps actba, anticorps inhba, anticorps inhbaa-001, anticorps edf, anticorps frp, anticorps INHB, anticorps inhbal, anticorps zgc:158348, anticorps inhibin beta A subunit, anticorps inhibin beta-A, anticorps inhibin, beta Aa, anticorps inhibin beta A, anticorps inhibin, beta Ab, anticorps INHBA, anticorps Inhba, anticorps inhbaa, anticorps inhba, anticorps inhbab
- Sujet
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The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
Alias Symbols: EDF, FRP
Protein Interaction Partner: ACVRL1, ACVR2B, ACVR2A, ACVR1, FST, IGSF1, CHRDL2, FSTL3, IGFBP7, ACVR1B, INHBC, TGFBR3, INHBB, INHA, INHBA, ENG,
Protein Size: 426 - Poids moléculaire
- 44 kDa
- ID gène
- 3624
- NCBI Accession
- NM_002192, NP_002183
- UniProt
- P08476
- Pathways
- Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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