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INHBA anticorps (N-Term)

INHBA Reactivité: Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chévre, Chien, Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785821
  • Antigène Voir toutes INHBA Anticorps
    INHBA (Inhibin, beta A (INHBA))
    Épitope
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 59
    • 29
    • 24
    • 9
    • 8
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Boeuf (Vache), Porc, Cheval, Mouton, Chévre, Chien, Lapin
    Hôte
    • 79
    • 11
    Lapin
    Clonalité
    • 79
    • 12
    Polyclonal
    Conjugué
    • 49
    • 16
    • 11
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp INHBA est non-conjugé
    Application
    • 79
    • 44
    • 34
    • 22
    • 21
    • 14
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    CPSCALAALP KDVPNSQPEM VEAVKKHILN MLHLKKRPDV TQPVPKAALL
    Homologie
    Cow: 100%, Dog: 93%, Goat: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against INHBA. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human INHBA
    Top Product
    Discover our top product INHBA Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 426 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ndiaye, Castonguay, Benoit, Silversides, Lussier: "Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells." dans: Journal of ovarian research, Vol. 9, Issue 1, pp. 71, (2016) (PubMed).

  • Antigène
    INHBA (Inhibin, beta A (INHBA))
    Autre désignation
    INHBA (INHBA Produits)
    Synonymes
    anticorps EDF, anticorps FRP, anticorps actba, anticorps inhba, anticorps inhbaa-001, anticorps edf, anticorps frp, anticorps INHB, anticorps inhbal, anticorps zgc:158348, anticorps inhibin beta A subunit, anticorps inhibin beta-A, anticorps inhibin, beta Aa, anticorps inhibin beta A, anticorps inhibin, beta Ab, anticorps INHBA, anticorps Inhba, anticorps inhbaa, anticorps inhba, anticorps inhbab
    Sujet
    The inhibin beta A subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta A subunit forms a homodimer, activin A, and also joins with a beta B subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion. Finally, it has been shown that the beta A subunit mRNA is identical to the erythroid differentiation factor subunit mRNA and that only one gene for this mRNA exists in the human genome.
    Alias Symbols: EDF, FRP
    Protein Interaction Partner: ACVRL1, ACVR2B, ACVR2A, ACVR1, FST, IGSF1, CHRDL2, FSTL3, IGFBP7, ACVR1B, INHBC, TGFBR3, INHBB, INHA, INHBA, ENG,
    Protein Size: 426
    Poids moléculaire
    44 kDa
    ID gène
    3624
    NCBI Accession
    NM_002192, NP_002183
    UniProt
    P08476
    Pathways
    Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Autophagy
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