Galectin 3 anticorps (N-Term)

N° du produit ABIN2785832

Détail du produit anti-Galectin 3 anticorps

Antigène: Galectin 3 (LGALS3)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Lapin, Chien, Porc, Boeuf (Vache), Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Galectin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 250 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Galectin 3 (ABIN2785832)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: LGALS3 (LGALS3 Produits)

Synonymes: anticorps CBP 35, anticorps Gal-3, anticorps Galectin-3, anticorps leg3, anticorps galactoside-binding, anticorps galectin-3, anticorps lectin, anticorps soluble, anticorps CBP35, anticorps GAL3, anticorps GALBP, anticorps GALIG, anticorps L31, anticorps LGALS2, anticorps MAC2, anticorps MGC52947, anticorps MGC75803, anticorps LGALS3, anticorps gal-3, anticorps GBP, anticorps L-34, anticorps Mac-2, anticorps gal3, anticorps galectin 3, anticorps Galectin-3, anticorps avian beta-defensin 3, anticorps lectin, galactoside-binding, soluble, 3 L homeolog, anticorps lectin, galactoside-binding, soluble, 3, anticorps galectin 2, anticorps lectin, galactose binding, soluble 3, anticorps LGALS3, anticorps leg3, anticorps AvBD3, anticorps lgals3.L, anticorps lgals3, anticorps LGALS2, anticorps Lgals3

Classe de substances: Chemical

Sujet: LGALS3 is a galactose-specific lectin which binds IgE. IT may mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, it is required for terminal differentiation of columnar epithelial cells during early embryogenesis.
Alias Symbols: CBP35, GAL3, GALBP, GALIG, LGALS2, MAC2, L31
Protein Interaction Partner: PRR13, SS18L1, PPIG, LGALS3, GOLGA2, MAP1LC3A, SQSTM1, RAB7A, LAMP1, EGFR, CFTR, PAXIP1, BARD1, AGPS, IGBP1, GTF2I, CLNS1A, APP, SLC25A5, ACTA1, MYOC, LGALS3BP, CYHR1, GEMIN4, SUFU, CUBN, CSNK1A1, LIM2, FCGR2A, ELN, MMP2, CSNK2A2, CSNK2A1, C1GALT1C1, LGAL
Protein Size: 250

Poids moléculaire: 26 kDa

ID gène: 3958

NCBI Accession: NM_002306, NP_002297

UniProt: P17931

Pathways: Signalisation RTK