Galectin 3 anticorps (N-Term)

N° du produit ABIN2785832

Il existe 1 publication pour ce produit. L’anticorps anti-Galectin 3 Polyclonal Lapin est utilisé pour la détection de Galectin 3 dans des échantillons de Humain, Souris, Rat, Lapin, Porc, Boeuf (Vache), Chien, Cobaye et Cheval. Il a été validé pour WB et IHC.

Aperçu rapide pour Galectin 3 anticorps (N-Term) (ABIN2785832)

Antigène: Galectin 3 (LGALS3)

Reactivité: Humain, Souris, Rat, Lapin, Porc, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Galectin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Galectin 3 anticorps

Épitope: N-Term

Fonction: LGALS3 Antibody - N-terminal region

Séquence: GASYPGAYPG QAPPGAYPGQ APPGAYPGAP GAYPGAPAPG VYPGPPSGPG

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against LGALS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LGALS3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54688-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Galectin 3 (ABIN2785832)

Guha, Bandyopadhyaya, Polumuri, Chumsri, Gade, Kalvakolanu, Ahmed et al.: "Nicotine promotes apoptosis resistance of breast cancer cells and enrichment of side population cells with cancer stem cell-like properties via a signaling cascade involving galectin-3, α9 nicotinic ..." dans: Breast cancer research and treatment, Vol. 145, Issue 1, pp. 5-22, (2014) (PubMed).

Détails sur Galectin 3

Antigène: Galectin 3 (LGALS3)

Autre désignation: LGALS3

Sujet:

Background Information: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.

Gene Name: galectin 3

Alternative Symbols: L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2

Protein Name: galectin-3

Poids moléculaire: 26kDa

ID gène: 3958

NCBI Accession: NP_002297

UniProt: P17931

Pathways: Signalisation RTK