IDH3G anticorps (C-Term)

N° du produit ABIN2785851

L’anticorps anti-IDH3G Polyclonal Lapin est utilisé pour la détection de IDH3G dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae, Lapin, Cobaye et Chévre. Il a été validé pour WB.

Aperçu rapide pour IDH3G anticorps (C-Term) (ABIN2785851)

Antigène: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae, Lapin, Cobaye, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3G est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IDH3G anticorps

Épitope: C-Term

Fonction: IDH3G Antibody - C-terminal region

Séquence: YMTRHNNLDL VIIREQTEGE YSSLEHEVRP QKLGEGKDED GREVELLVSL

Homologie: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IDH3B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of human IDH3G

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP54721-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur IDH3G

Antigène: IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))

Autre désignation: IDH3G

Sujet:

Background Information: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.

Gene Name: isocitrate dehydrogenase 3 (NAD+) gamma

Alternative Symbols: H-IDHG

Protein Name: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial

Poids moléculaire: 22kDa

ID gène: 3421

NCBI Accession: NP_004126

UniProt: P51553