GRK5 anticorps (Middle Region)

N° du produit ABIN2785866

Cet anticorps Lapin Polyclonal détecte spécifiquement GRK5 dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio), Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour GRK5 anticorps (Middle Region) (ABIN2785866)

Antigène: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Poisson zèbre (Danio rerio), Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRK5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GRK5 anticorps

Épitope: Middle Region

Séquence: FYAAEILCGL EDLHRENTVY RDLKPENILL DDYGHIRISD LGLAVKIPEG

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against GRK5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human GRK5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 590 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur GRK5

Antigène: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Autre désignation: GRK5

Sujet: GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPRK5
Protein Interaction Partner: TBXA2R, USP47, C1QBP, YWHAB, XRCC5, UBTF, UBC, TUFM, NR2F1, TCOF1, SRPK1, SPTBN1, SPTAN1, SMARCA1, SKP1, SRSF1, RPL4, RPL3, RBMS1, PSMD11, PSMD2, PSMC6, PSMC2, PSMC1, PRKDC, PPP2R2A, PNN, PIP4K2A, PIP, NFIB, NCL, NCBP1, MYO9B, MYO1C, MYH10, MYH9, MYCN, MA
Protein Size: 590

Poids moléculaire: 68 kDa

ID gène: 2869

NCBI Accession: NM_005308, NP_005299

UniProt: P34947

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling