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GRF2 anticorps (C-Term)

RAPGEF1 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785868
  • Antigène Voir toutes GRF2 (RAPGEF1) Anticorps
    GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
    Épitope
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 37
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Poisson zèbre (Danio rerio)
    Hôte
    • 29
    • 6
    • 2
    Lapin
    Clonalité
    • 31
    • 6
    Polyclonal
    Conjugué
    • 28
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRF2 est non-conjugé
    Application
    • 20
    • 14
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against RAPGEF1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human RAPGEF1
    Top Product
    Discover our top product RAPGEF1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1077 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))
    Autre désignation
    RAPGEF1 (RAPGEF1 Produits)
    Synonymes
    anticorps C3G, anticorps GRF2, anticorps Link-GEFII, anticorps 4932418O06Rik, anticorps Grf2, anticorps RAPGEF1, anticorps C3G-1, anticorps C3G-2, anticorps C3g, anticorps rapgef1, anticorps zgc:56372, anticorps Rap guanine nucleotide exchange factor 1, anticorps Rap guanine nucleotide exchange factor like 1, anticorps Rap guanine nucleotide exchange factor (GEF) 1, anticorps Rap guanine nucleotide exchange factor 1 S homeolog, anticorps Rap guanine nucleotide exchange factor (GEF) 1b, anticorps RAPGEF1, anticorps RAPGEFL1, anticorps Rapgef1, anticorps rapgef1.S, anticorps rapgef1, anticorps rapgef1b, anticorps Rapgefl1
    Sujet
    RAPGEF1 is a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
    Alias Symbols: C3G, DKFZp781P1719, GRF2
    Protein Interaction Partner: UBC, MBIP, SLC20A1, ATXN1, RPS15, CRKL, CRK, CBL, GRB2, NEDD9, RHOQ, BCAR1, SHC1, RRAS2, HRAS, RAP1B, HCK, RAP1A,
    Protein Size: 1077
    Poids moléculaire
    120 kDa
    ID gène
    2889
    NCBI Accession
    NM_005312, NP_005303
    UniProt
    Q13905
    Pathways
    Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
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