Lactate Dehydrogenase A anticorps (Middle Region)
Aperçu rapide pour Lactate Dehydrogenase A anticorps (Middle Region) (ABIN2785876)
Antigène
Voir toutes Lactate Dehydrogenase A (LDHA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH
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Homologie
- Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human LDHA
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 332 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." dans: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).
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: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." dans: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).
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- Lactate Dehydrogenase A (LDHA)
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Autre désignation
- LDHA
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Sujet
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LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
Protein Size: 332 -
Poids moléculaire
- 37 kDa
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ID gène
- 3939
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NCBI Accession
- NM_005566, NP_005557
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UniProt
- P00338
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Pathways
- L'effet Warburg
Antigène
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