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Lactate Dehydrogenase A anticorps (Middle Region)

Cet anticorps Lapin Polyclonal détecte spécifiquement Lactate Dehydrogenase A dans WB et IHC. Il présente une réactivité envers Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Chien, Chévre et Poisson zèbre (Danio rerio) et a été mentionné dans 1 publication.
N° du produit ABIN2785876

Aperçu rapide pour Lactate Dehydrogenase A anticorps (Middle Region) (ABIN2785876)

Antigène

Voir toutes Lactate Dehydrogenase A (LDHA) Anticorps
Lactate Dehydrogenase A (LDHA)

Reactivité

  • 81
  • 36
  • 27
  • 10
  • 6
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Cobaye, Chien, Chévre, Poisson zèbre (Danio rerio)

Hôte

  • 89
  • 21
  • 6
  • 5
Lapin

Clonalité

  • 97
  • 22
Polyclonal

Conjugué

  • 60
  • 17
  • 13
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Cet anticorp Lactate Dehydrogenase A est non-conjugé

Application

  • 85
  • 46
  • 44
  • 32
  • 24
  • 22
  • 10
  • 9
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 17
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Séquence

    PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH

    Homologie

    Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%

    Attributs du produit

    This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the middle region of human LDHA
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 332 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." dans: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

  • Antigène

    Lactate Dehydrogenase A (LDHA)

    Autre désignation

    LDHA

    Sujet

    LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
    Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
    Protein Size: 332

    Poids moléculaire

    37 kDa

    ID gène

    3939

    NCBI Accession

    NM_005566, NP_005557

    UniProt

    P00338

    Pathways

    L'effet Warburg
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