PHGDH anticorps (Middle Region)

N° du produit ABIN2785892

Cet anticorps Lapin Polyclonal détecte spécifiquement PHGDH dans WB. Il présente une réactivité envers Humain, Souris, Rat, Cheval, Porc, Lapin, Chien, Boeuf (Vache), Cobaye et Poisson zèbre (Danio rerio).

Aperçu rapide pour PHGDH anticorps (Middle Region) (ABIN2785892)

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivité: Humain, Souris, Rat, Cheval, Porc, Lapin, Chien, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHGDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PHGDH anticorps

Épitope: Middle Region

Séquence: CAGAALDVFT EEPPRDRALV DHENVISCPH LGASTKEAQS RCGEEIAVQF

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PHGDH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PHGDH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 533 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PHGDH

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Autre désignation: PHGDH

Sujet: 3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].
Alias Symbols: 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, ITSN1, ROM1, RPAP3, EPN1, SUMO1, NEDD8, MDM2, SUZ12, RNF2, EZH2, BMI1, FBXO6, TARDBP, EGFR, UBD, CLN5, CLN3, CDK2, PIAS4, FN1, TRAF3IP1, ECT2, MDC1, UQCC3, VASN, TRIM55, SMU1, TRA2A, ADNP, NCSTN, U2AF2, TCERG1, UTP14A, SRSF10, SAP1
Protein Size: 533

Poids moléculaire: 57 kDa

ID gène: 26227

NCBI Accession: NM_006623, NP_006614

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, L'effet Warburg