PHGDH anticorps (Middle Region)

N° du produit ABIN503573

L’anticorps anti-PHGDH Polyclonal Lapin est utilisé pour la détection de PHGDH dans des échantillons de Humain, Souris, Rat, Cheval, Porc, Lapin et Chien. Il a été validé pour WB.

Aperçu rapide pour PHGDH anticorps (Middle Region) (ABIN503573)

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivité: Humain, Souris, Rat, Cheval, Porc, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHGDH est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PHGDH anticorps

Épitope: Middle Region

Séquence: SLKNAGNCLS PAVIVGLLKE ASKQADVNLV NAKLLVKEAG LNVTTSHSPA

Homologie: Dog: 92%, Horse: 83%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PHGDH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PHGDH

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 533 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PHGDH

Antigène: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Autre désignation: PHGDH

Sujet: 3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.3-Phosphoglycerate dehydrogenase (PHGDH, EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.[supplied by OMIM].
Alias Symbols: 3-PGDH, 3PGDH, MGC3017, PDG, PGAD, PGD, PGDH, SERA
Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, ITSN1, ROM1, RPAP3, EPN1, SUMO1, NEDD8, MDM2, SUZ12, RNF2, EZH2, BMI1, FBXO6, TARDBP, EGFR, UBD, CLN5, CLN3, CDK2, PIAS4, FN1, TRAF3IP1, ECT2, MDC1, UQCC3, VASN, TRIM55, SMU1, TRA2A, ADNP, NCSTN, U2AF2, TCERG1, UTP14A, SRSF10, SAP1
Protein Size: 533

Poids moléculaire: 57 kDa

ID gène: 26227

NCBI Accession: NM_006623, NP_006614

UniProt: O08651

Pathways: Metabolism of Steroid Hormones and Vitamin D, L'effet Warburg