POLM anticorps (Middle Region)

N° du produit ABIN2785958

Détail du produit anti-POLM anticorps

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Épitope: Middle Region

Reactivité: Humain, Souris, Porc, Lapin, Rat, Cheval, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLM est non-conjugé

Application: Western Blotting (WB)

Séquence: LRRFSRKEKG LWLNSHGLFD PEQKTFFQAA SEEDIFRHLG LEYLPPEQRN

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against POLM. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human POLM

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 494 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur POLM

Antigène: POLM (Polymerase (DNA Directed), mu (POLM))

Autre désignation: POLM (POLM Produits)

Synonymes: anticorps polmu, anticorps zgc:56122, anticorps POLM, anticorps Pol Mu, anticorps Tdt-N, anticorps AI462166, anticorps B230309I03Rik, anticorps polymerase (DNA directed), mu, anticorps DNA polymerase mu, anticorps polm, anticorps POLM, anticorps CC1G_09351, anticorps VDBG_09335, anticorps Polm

Sujet: POLM seems to act as an Ig mutase which is responsible for immunoglobulin (Ig) gene hypermutation.
Alias Symbols: Tdt-N, Pol Mu
Protein Interaction Partner: CEP55, IKZF3, PNMA1, PCNA, UBE2C, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 494

Poids moléculaire: 55 kDa

ID gène: 27434

NCBI Accession: NM_013284, NP_037416

UniProt: Q9NP87

Pathways: Réparation de l'ADN, Production of Molecular Mediator of Immune Response