CARD8 anticorps (N-Term)

N° du produit ABIN2786065

L’anticorps anti-CARD8 Polyclonal Lapin est utilisé pour la détection de CARD8 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour CARD8 anticorps (N-Term) (ABIN2786065)

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CARD8 anticorps

Épitope: N-Term

Fonction: CARD8 Antibody - N-terminal region

Séquence: LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CARD8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARD8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55119-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CARD8

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Autre désignation: CARD8

Sujet:

Background Information: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.

Gene Name: caspase recruitment domain family, member 8

Alternative Symbols: NDPP, DACAR, DAKAR, NDPP1, TUCAN, CARDINAL

Protein Name: Caspase recruitment domain-containing protein 8

Poids moléculaire: 31kDa

ID gène: 22900

UniProt: Q9Y2G2

Pathways: Positive Regulation of Endopeptidase Activity