CARD8 anticorps (N-Term)

N° du produit ABIN2786065

Détail du produit anti-CARD8 anticorps

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CARD8 est non-conjugé

Application: Western Blotting (WB)

Séquence: LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID

Homologie: Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CARD8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human CARD8

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CARD8

Antigène: CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Autre désignation: CARD8 (CARD8 Produits)

Synonymes: anticorps CARD8, anticorps CARDINAL, anticorps DACAR, anticorps DAKAR, anticorps NDPP, anticorps NDPP1, anticorps TUCAN, anticorps caspase recruitment domain family, member 8, anticorps caspase recruitment domain-containing protein 8, anticorps caspase recruitment domain family member 8, anticorps CARD8, anticorps LOC718594

Sujet: The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Protein Interaction Partner: ELAVL1, CARD16, CARD8, CARD18, NLRP2, NLRP3, FHL2, CASP9, IKBKG, CASP1, CARD6,
Protein Size: 286

Poids moléculaire: 31 kDa

ID gène: 22900

Pathways: Positive Regulation of Endopeptidase Activity