KIFAP3 anticorps (Middle Region)

N° du produit ABIN2786068

L’anticorps Lapin Polyclonal anti-KIFAP3 a été validé pour WB. Il convient pour détecter KIFAP3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien.

Aperçu rapide pour KIFAP3 anticorps (Middle Region) (ABIN2786068)

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIFAP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIFAP3 anticorps

Épitope: Middle Region

Séquence: WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KIFAP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 792 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KIFAP3

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Autre désignation: KIFAP3

Sujet: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.
Alias Symbols: FLJ22818, KAP3, SMAP, Smg-GDS, dJ190I16.1, KAP-3
Protein Interaction Partner: NAA10, NCF2, UBC, PEX19, RBFOX1, KIF3A, VHL, RANBP2, MEST, DISC1, NIPSNAP3A, NUDT21, AR, RAP1GDS1, MINK1, SMC3, KIF3B, KIFAP3, MAP3K10, RPGR, SRC, APC, MAP3K11,
Protein Size: 792

Poids moléculaire: 91 kDa

ID gène: 22920

NCBI Accession: NM_014970, NP_055785

UniProt: Q92845

Pathways: Signalisation Hedgehog, Sensory Perception of Sound