KIFAP3 anticorps (Middle Region)

N° du produit ABIN2786068

L’anticorps anti-KIFAP3 Polyclonal Lapin est utilisé pour la détection de KIFAP3 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin et Chien. Il a été validé pour WB.

Aperçu rapide pour KIFAP3 anticorps (Middle Region) (ABIN2786068)

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIFAP3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KIFAP3 anticorps

Épitope: Middle Region

Fonction: KIFAP3 Antibody - middle region

Séquence: WLEMVESRQM DESEQYLYGD DRIEPYIHEG DILERPDLFY NSDGLIASEG

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KIFAP3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human KIFAP3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55127-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur KIFAP3

Antigène: KIFAP3 (Kinesin Associated Protein 3 (KIFAP3))

Autre désignation: KIFAP3

Sujet:

Background Information: The small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras, one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 'Armadillo' repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein.

Gene Name: Kinesin-associated protein 3

Alternative Symbols: FLA3, KAP3, SMAP, KAP-1, KAP-3, Smg-GDS, dJ190I16.1

Protein Name: Kinesin-associated protein 3

Poids moléculaire: 91kDa

ID gène: 22920

NCBI Accession: NP_055785

UniProt: Q92845

Pathways: Signalisation Hedgehog, Sensory Perception of Sound