SPG20 anticorps (Middle Region)

N° du produit ABIN2786078

Cet anticorps anti-SPG20 est un anticorps Lapin Polyclonal détectant SPG20 dans WB. Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour SPG20 anticorps (Middle Region) (ABIN2786078)

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPG20 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SPG20 anticorps

Épitope: Middle Region

Séquence: ASWVSWGLVK GAEITGKAIQ KGASKLRERI QPEEKPVEVS PAVTKGLYIA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against SPG20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SPG20

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 666 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SPG20

Antigène: SPG20 (Spastic Paraplegia 20 (Troyer Syndrome) (SPG20))

Autre désignation: SPG20

Sujet: This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Alias Symbols: KIAA0610, SPARTIN, TAHCCP1
Protein Interaction Partner: UBC, WWOX, ITCH, PLIN3, SMURF2, ZFYVE9, APP, EPS15, SMURF1, WWP2, WWP1, SUMO2, KLC2, AIFM1, VIM, NCL, LMNB1, KPNB1, KIF5B, HSPD1, HSPA9, HSPA5, HADHA, ACSL4, ACSL3, DYNC1H1, COPA, CLTC, TUBA1A,
Protein Size: 666

Poids moléculaire: 73 kDa

ID gène: 23111

NCBI Accession: NM_015087, NP_055902

UniProt: Q8N0X7

Pathways: Regulation of Cell Size, SARS-CoV-2 Protein Interactome