NKIRAS1 anticorps (N-Term)

N° du produit ABIN2786171

L’anticorps anti-NKIRAS1 Polyclonal Lapin est utilisé pour la détection de NKIRAS1 dans des échantillons de Humain, Souris, Rat, Chien, Chévre, Cheval, Lapin, Boeuf (Vache), Cobaye et Poisson zèbre (Danio rerio). Il a été validé pour WB.

Aperçu rapide pour NKIRAS1 anticorps (N-Term) (ABIN2786171)

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reactivité: Humain, Souris, Rat, Chien, Chévre, Cheval, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKIRAS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NKIRAS1 anticorps

Épitope: N-Term

Fonction: NKIRAS1 Antibody - N-terminal region

Séquence: CETMEDVYMA SVETDRGVKE QLHLYDTRGL QEGVELPKHY FSFADGFVLV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against NKIRAS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NKIRAS1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55370-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur NKIRAS1

Antigène: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Autre désignation: NKIRAS1

Sujet:

Background Information: NKIRAS1 is an atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. NKIRAS1 may act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Gene Name: NFKB inhibitor interacting Ras-like 1

Alternative Symbols: KBRAS1, kappaB-Ras1

Protein Name: NF-kappa-B inhibitor-interacting Ras-like protein 1

Poids moléculaire: 22kDa

ID gène: 28512

NCBI Accession: NP_065078

UniProt: Q9NYS0