FANCE anticorps (Middle Region)

N° du produit ABIN2786176

Cet anticorps anti-FANCE est un anticorps Lapin Polyclonal détectant FANCE dans WB. Adapté pour Humain, Boeuf (Vache), Cheval, Porc, Lapin et Chien.

Aperçu rapide pour FANCE anticorps (Middle Region) (ABIN2786176)

Antigène: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Reactivité: Humain, Boeuf (Vache), Cheval, Porc, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FANCE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FANCE anticorps

Épitope: Middle Region

Séquence: SPQAPDPEEE ENRDSQQPGK RRKDSEEEAA SPEGKRVPKR LRCWEEEEDH

Homologie: Cow: 86%, Dog: 79%, Horse: 85%, Human: 100%, Pig: 79%, Rabbit: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FANCE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FANCE

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 536 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FANCE

Antigène: FANCE (Fanconi Anemia, Complementation Group E (FANCE))

Autre désignation: FANCE

Sujet: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group E. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FACE, FAE
Protein Interaction Partner: APITD1, STRA13, UBC, FANCG, FANCD2, FANCC, FANCA, FANCM, C1orf86, ELAVL1, Erh, FANCF, CHEK1, HES1, PCNA, BRCA2,
Protein Size: 536

Poids moléculaire: 59 kDa

ID gène: 2178

NCBI Accession: NM_021922, NP_068741

UniProt: Q9HB96

Pathways: Réparation de l'ADN