K-RAS anticorps (N-Term)
Aperçu rapide pour K-RAS anticorps (N-Term) (ABIN2786191)
Antigène
Voir toutes K-RAS (KRAS) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- TEYKLVVVGA GGVGKSALTI QLIQNHFVDE YDPTIEDSYR KQVVIDGETC
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Specificité
- 100 % homologous to human KRAS, NRAS and HRAS.
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against KRAS. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human KRAS
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 189 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- K-RAS (KRAS) (GTPase Kras (KRAS))
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Autre désignation
- KRAS
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Sujet
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KRAS is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma.
Alias Symbols: C-K-RAS, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2
Protein Interaction Partner: RBPMS, UBC, PSMA3, ARAF, MDFI, TRAF6, BCL2, BTRC, RAF1, MAPK1, PHB, DDX50, EGLN1, DDX47, RALGDS, RGL2, PIK3R2, LPAR1, ADH6, APP, ELAVL1, CALM1, IGSF21, CCT7, PDE4DIP, DNAJA3, EEF1A1, RASGRF2, RASSF2, RAP1GDS1, RASGRP2, RASSF5, SHOC2, PGGT1B, PIK3CG, EPB42
Protein Size: 189 -
Poids moléculaire
- 22 kDa
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ID gène
- 3845
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NCBI Accession
- NM_033360, NP_203524
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UniProt
- P01111
Antigène
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