SKA1 anticorps (Middle Region)

N° du produit ABIN2786219

L’anticorps anti-SKA1 Polyclonal Lapin est utilisé pour la détection de SKA1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc et Lapin. Il a été validé pour WB.

Aperçu rapide pour SKA1 anticorps (Middle Region) (ABIN2786219)

Antigène: SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SKA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SKA1 anticorps

Épitope: Middle Region

Fonction: Ska1 Antibody - middle region

Séquence: LLNKFELEIQ YQEQTNSSLK ELCESLREEC EDVEHLKEHV PPHLPQVTAT

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Ska1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP55460-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SKA1

Antigène: SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))

Autre désignation: Ska1

Sujet:

Background Information: Ska1 is a Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. It is required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.

Gene Name: Spindle and kinetochore associated complex subunit 1

Alternative Symbols: AV117428, 2810433K01Rik

Protein Name: Spindle and kinetochore-associated protein 1

Poids moléculaire: 28kDa

ID gène: 66468

NCBI Accession: NP_079857

UniProt: Q9CPV1

Pathways: M Phase