FBXW8 anticorps (Middle Region)

N° du produit ABIN2786276

Cet anticorps anti-FBXW8 Polyclonal Lapin (ABIN2786276) détecte spécifiquement FBXW8 dans WB. L’anticorps est réactif avec des échantillons de Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval et Chien.

Aperçu rapide pour FBXW8 anticorps (Middle Region) (ABIN2786276)

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Lapin, Cobaye, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXW8 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXW8 anticorps

Épitope: Middle Region

Séquence: RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against FBXW8. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXW8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 598 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXW8

Antigène: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Autre désignation: FBXW8

Sujet: FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.
Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
Protein Interaction Partner: MAP4K1, CUL1, TBC1D3, CUL7, UBE2D3, SKP1, IRS1, REST, CCND1, CUL4A, DDB1, UBC, CCDC8, GORASP1, OBSL1, CCT6B, CCT2, CCT7, TRIP13, PDCD5, CUL2, VBP1, CCT3, PFDN5, NFKBIA, CCT6A, BCL3, BTRC, SKP2, HSP90AA1, HSPA4, FBXO4, FBXW8, FBXW2, MYC, RBX1, UBI4, EP300,
Protein Size: 598

Poids moléculaire: 67 kDa

ID gène: 26259

NCBI Accession: NM_153348, NP_699179

UniProt: Q8N3Y1