FBXO33 anticorps (Middle Region)

N° du produit ABIN2786447

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXO33 dans WB. Il présente une réactivité envers Rat, Humain, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour FBXO33 anticorps (Middle Region) (ABIN2786447)

Antigène: FBXO33 (F-Box Protein 33 (FBXO33))

Reactivité: Rat, Humain, Souris, Boeuf (Vache), Chien, Cobaye, Lapin, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO33 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FBXO33 anticorps

Épitope: Middle Region

Séquence: VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FBXO33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXO33

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 555 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXO33

Antigène: FBXO33 (F-Box Protein 33 (FBXO33))

Autre désignation: FBXO33

Sujet: FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx33, c14_5247, BMND12
Protein Interaction Partner: CUL1, YBX1, UBC,
Protein Size: 555

Poids moléculaire: 62 kDa

ID gène: 254170

NCBI Accession: NM_203301, NP_976046

UniProt: Q7Z6M2