FBXO33 anticorps (Middle Region)

N° du produit ABIN2786447

Détail du produit anti-FBXO33 anticorps

Antigène: FBXO33 (F-Box Protein 33 (FBXO33))

Épitope: Middle Region

Reactivité: Rat, Humain, Souris, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO33 est non-conjugé

Application: Western Blotting (WB)

Séquence: VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against FBXO33. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FBXO33

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 555 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FBXO33

Antigène: FBXO33 (F-Box Protein 33 (FBXO33))

Autre désignation: FBXO33 (FBXO33 Produits)

Synonymes: anticorps FBXO33, anticorps BMND12, anticorps Fbx33, anticorps c14_5247, anticorps 5730501N20Rik, anticorps AI642135, anticorps F-box protein 33, anticorps F-box protein 33 S homeolog, anticorps FBXO33, anticorps fbxo33, anticorps fbxo33.S, anticorps Fbxo33

Sujet: FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: Fbx33, c14_5247, BMND12
Protein Interaction Partner: CUL1, YBX1, UBC,
Protein Size: 555

Poids moléculaire: 62 kDa

ID gène: 254170

NCBI Accession: NM_203301, NP_976046

UniProt: Q7Z6M2