PDE6A anticorps (N-Term)

N° du produit ABIN2786520

Cet anticorps anti-PDE6A Polyclonal Lapin (ABIN2786520) détecte spécifiquement PDE6A dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio) et Lapin.

Aperçu rapide pour PDE6A anticorps (N-Term) (ABIN2786520)

Antigène: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE6A est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PDE6A anticorps

Épitope: N-Term

Fonction: PDE6A Antibody - N-terminal region

Séquence: YRTRNGIAEL ATRLFNVHKD AVLEDCLVMP DQEIVFPLDM GIVGHVAHSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PDE6A. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of human PDE6A

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56111-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur PDE6A

Antigène: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Autre désignation: PDE6A

Sujet:

Background Information: This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Gene Name: phosphodiesterase 6A

Alternative Symbols: PDEA, RP43, CGPR-A

Protein Name: rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

Poids moléculaire: 85kDa

ID gène: 5145

NCBI Accession: NP_000431

UniProt: P16499

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction