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PDE6A anticorps (N-Term)

PDE6A Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2786520
  • Antigène Voir toutes PDE6A Anticorps
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Épitope
    • 7
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    N-Term
    Reactivité
    • 24
    • 10
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin
    Hôte
    • 24
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 12
    • 3
    • 3
    • 2
    • 2
    • 2
    Cet anticorp PDE6A est non-conjugé
    Application
    • 21
    • 17
    • 9
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Séquence
    YRTRNGIAEL ATRLFNVHKD AVLEDCLVMP DQEIVFPLDM GIVGHVAHSK
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PDE6A. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N-terminal region of human PDE6A
    Top Product
    Discover our top product PDE6A Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeat freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))
    Autre désignation
    PDE6A (PDE6A Produits)
    Synonymes
    anticorps si:bz1d10.3, anticorps si:rp71-1d10.3, anticorps CGPR-A, anticorps PDEA, anticorps RP43, anticorps Pdea, anticorps nmf282, anticorps phosphodiesterase 6A, cGMP-specific, rod, alpha, anticorps phosphodiesterase 6A, anticorps pde6a, anticorps PDE6A, anticorps Pde6a
    Sujet
    This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
    Alias Symbols: PDEA, RP43, CGPR-A
    Protein Size: 779
    Poids moléculaire
    85 kDa
    ID gène
    5145
    NCBI Accession
    NM_000440, NP_000431
    UniProt
    P16499
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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